Baked Salmon Cajun Spice

Baked salmon with Cajun seasoning: a flaky, moist fillet, redolent with spicy Cajun spices, ready to eat. Save
Baked salmon with Cajun seasoning: a flaky, moist fillet, redolent with spicy Cajun spices, ready to eat. | recipesbyleticia.com

This dish features skinless salmon fillets seasoned with a vibrant Cajun spice blend including smoked paprika, cayenne, and herbs. Lightly brushed with olive oil, the fillets bake quickly at 400°F until tender and flaky. Serve with fresh lemon slices and parsley for a bright finish. The bold seasoning delivers a balanced heat that can be adjusted to taste, providing a healthy, flavorful meal ideal for weeknight dinners. Easily paired with steamed rice or roasted veggies, this preparation highlights the natural moisture and rich texture of salmon.

I was standing in front of the spice cabinet on a Tuesday night, too tired for anything complicated but craving something bold. That's when I grabbed the paprika, cayenne, and a few other jars and started shaking them into a bowl. What came out of the oven twenty minutes later changed how I think about weeknight dinners.

The first time I made this for friends, I watched them go quiet after the first bite, then immediately ask for the recipe. One of them started making it every Sunday. There's something about the smoky, spicy crust against the tender fish that just works, every single time.

Ingredients

  • Salmon fillets: Look for thick, evenly cut pieces so they cook at the same rate, and always pat them completely dry or the seasoning won't stick.
  • Smoked paprika: This is the secret to that deep, almost grilled flavor without ever turning on the grill.
  • Garlic powder and onion powder: They create a savory base that balances the heat and keeps the spice blend from tasting one dimensional.
  • Oregano and thyme: Dried herbs add an earthy backbone that makes the seasoning feel complete, not just spicy.
  • Cayenne pepper: Start with less if you are cautious, you can always add more heat but you cannot take it away.
  • Olive oil: A light brush helps the spices cling and creates a beautiful caramelized edge.
  • Lemon: The acidity cuts through the richness and wakes up every flavor on the plate.
  • Fresh parsley: A handful of green at the end makes it look and taste brighter.

Instructions

Preheat and Prep:
Set your oven to 400°F and line a baking sheet with parchment paper. This step matters more than you think because it prevents sticking and makes cleanup effortless.
Mix the Cajun Seasoning:
Combine smoked paprika, garlic powder, onion powder, oregano, thyme, cayenne, black pepper, and salt in a small bowl. The smell alone will tell you this is going to be good.
Dry and Oil the Salmon:
Pat each fillet completely dry with paper towels, then brush both sides lightly with olive oil. Moisture is the enemy of a good crust.
Season Generously:
Sprinkle the Cajun blend evenly over the top of each fillet and press gently so it sticks. Do not be shy, this is where the flavor lives.
Arrange and Bake:
Place the fillets on the prepared sheet with a little space between them. Bake for 12 to 15 minutes until the salmon flakes easily and the center is opaque.
Serve with Brightness:
Pull the pan out, squeeze fresh lemon over the top, and scatter parsley if you have it. Serve immediately while it is still hot and fragrant.
Golden-baked salmon with Cajun seasoning, served alongside bright lemon slices, looks incredibly flavorful. Save
Golden-baked salmon with Cajun seasoning, served alongside bright lemon slices, looks incredibly flavorful. | recipesbyleticia.com

I remember plating this for my mom, who usually only eats salmon when someone else cooks it. She took one bite, looked up, and said it tasted like something she would order out. That is when I knew this recipe was a keeper.

How to Adjust the Heat

If you are cooking for kids or anyone sensitive to spice, cut the cayenne in half or leave it out entirely. The smoked paprika and herbs will still deliver plenty of flavor. On the other hand, if you want more kick, add a pinch of red pepper flakes or an extra quarter teaspoon of cayenne.

What to Serve It With

This salmon pairs beautifully with steamed jasmine rice, roasted asparagus, or a simple arugula salad with lemon vinaigrette. I have also served it over quinoa with sautéed spinach and it disappeared in minutes. Keep the sides light so the bold flavors of the fish can shine.

Storage and Meal Prep

Leftover salmon keeps well in the fridge for up to three days and tastes great cold on top of salads or grain bowls. You can also make the seasoning blend ahead and store it in a jar for up to three months, which makes this even faster on busy nights.

  • Reheat gently in a 300°F oven to avoid drying it out.
  • Try this seasoning on chicken thighs or roasted cauliflower for variety.
  • Double the spice mix and keep it handy for last minute flavor emergencies.
Enjoy this healthy, perfectly cooked baked salmon with Cajun seasoning, bursting with savory flavors. Save
Enjoy this healthy, perfectly cooked baked salmon with Cajun seasoning, bursting with savory flavors. | recipesbyleticia.com

This is the kind of recipe that makes you feel capable in the kitchen, even on your most exhausted days. Keep the spices stocked and the salmon in your freezer, and you will always have something impressive ready to go.

Common Questions

Reduce the cayenne pepper quantity in the Cajun seasoning to lower heat or omit it for a milder flavor.

Yes, trout or cod can be used as alternatives, adjusting baking time as needed for thickness.

Preheat oven to 400°F and bake on a lined sheet for 12-15 minutes until the flesh flakes easily with a fork.

Serve with lemon slices and chopped parsley. It pairs well with steamed rice, roasted vegetables, or a crisp salad.

Yes, keep the seasoning blend in an airtight container for up to 3 months to maintain freshness.

Baked Salmon Cajun Spice

Tender salmon fillets perfectly baked with a smoky Cajun spice blend, ready in under 30 minutes.

Prep 10m
Cook 15m
Total 25m
Servings 4
Difficulty Easy

Ingredients

Fish

  • 4 skinless salmon fillets, 6 oz (170 g) each

Cajun Seasoning Blend

  • 1 tablespoon smoked paprika
  • 1 teaspoon garlic powder
  • 1 teaspoon onion powder
  • 1 teaspoon dried oregano
  • 1 teaspoon dried thyme
  • 1 teaspoon cayenne pepper (adjust for heat)
  • ½ teaspoon black pepper
  • ½ teaspoon salt

Other

  • 2 tablespoons olive oil
  • 1 lemon, sliced (for serving)
  • Fresh parsley, chopped (optional, for garnish)

Instructions

1
Preheat oven: Preheat oven to 400°F. Line a baking sheet with parchment paper or foil.
2
Prepare Cajun seasoning: Combine all Cajun seasoning ingredients in a small bowl and mix thoroughly.
3
Prepare salmon: Pat salmon fillets dry with paper towels and brush both sides lightly with olive oil.
4
Apply seasoning: Evenly sprinkle Cajun seasoning over the top of each fillet, gently pressing to adhere.
5
Arrange fillets: Place seasoned salmon fillets on the prepared baking sheet spaced evenly.
6
Bake: Bake for 12 to 15 minutes, until salmon flakes easily with a fork and is opaque at the center.
7
Serve: Serve immediately with lemon slices and a garnish of fresh parsley if desired.
Additional Information

Equipment Needed

  • Baking sheet
  • Parchment paper or foil
  • Small mixing bowl
  • Pastry brush
  • Measuring spoons

Nutrition (Per Serving)

Calories 325
Protein 35g
Carbs 3g
Fat 18g

Allergy Information

  • Contains fish (salmon).
  • Naturally gluten-free and dairy-free.
  • Check spice blends for possible allergens or cross-contamination.
Leticia Fernández

Sharing easy, flavorful meals and practical cooking tips for home cooks and food lovers.